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芫花制剂中期妊娠引产的研究——黄芫花制剂和芫花萜对人及家兔妊娠子宫肌的直接作用

STUDIES ON INDUCTION OF ABORTION BY PREPARATIONS OF YUANHUA (WIKSTREEMIA, CHAMIAEDEPHAE MEISSA) IN MID-PREGNANCY——Direct Action of Huanyuanhua and Yuanhua Pertene on Human and Rabbit Uterus Muscle in Vitro

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【作者】 张珉王怀福于俊荣李荣秀王振海

【Author】 Zhang Min;Wang Huai-fu;Yu Jun-reng;Li Reng-xiu;Wang Zhen-hai Department of Physiology and Biochemistry, Family Planning Institute of Hebei Province, Shijiazhuang Department of Obstetrics and Gynaecology, Hebei Medical College Second Hospital

【机构】 河北省计划生育研究所河北医学院第二附属医院

【摘要】 本研究观察了黄芫花醇液和芫花萜对孕妇子宫肌条及黄芫花混悬液对妊娠和非妊娠家兔子宫肌条的直接作用。结果,黄芫花醇液可直接对人妊娠子宫肌条发挥作用,加强其收缩活动。芫花萜却不具这种功能,从而推测黄芫花除含有引产药—芫花萜外,尚含有可以直接引起子宫收缩的物质。家兔妊娠和非妊娠子宫对黄芫花混悬液的反应不同,前者收缩明显加强;后者收缩并无改变。表明妊娠子宫肌由于受较多的激素影响,其应激性有明显的提高。

【Abstract】 The results obtained in our experiment may be summarized as follows: (1) The present paper undertakes to report the direct action of the Alcohuan-yuanhua and Yuanhua Pertene on human pregnant uterus muscle strap and of Huanyuan-hua suspension on rabbit pregnant and nonpregnant uterus muscle strap. (2) The results of the experiments in vitro have clearly proved that Alcohuanyuanhuaexerted a direct effect on human pregnant uterus, strengthening its contraction, but YuanhuaPertene did not have such an effect. It is inferred that Huanyuanhua has two compositions:one is Yuanhua Pertene which can induce an abortive effect and the other a substance that candirectly induce contraction of the uterus. This substance exerts a positive action in abortion. (3) There is difference between the response of the rabbit pregnant and nonpregnantuterus muscle to Huanyuanhua suspension: the former makes the contraction of the uterusstronger while the latter does not affect the contraction. The results show that the irritabilityof the pregnant uterus muscle is distinctly raised owing to the effect of increased hormone.

【关键词】 Induced abortionMid-pregnancyYuankua
【Key words】 Induced abortionMid-pregnancyYuankua
  • 【文献出处】 生殖与避孕 ,Reproduction & Contraception , 编辑部邮箱 ,1984年03期
  • 【被引频次】3
  • 【下载频次】48
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