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侧脑室注射牛胰多肽对家兔糖耐量和血清胰岛素浓度的影响
EFFECT OF INTRACEREBRO-VENTRICULAR INJECTION OF BOVINE PANCREATIC POLYPEPTIDE(BPP)ON GLUCOSE TOLERANCE AND SERUM INSULIN CONCENTRATION IN RABBITS
【摘要】 在家兔侧脑室内微量注射牛胰多肽能增加其糖耐量及血清胰岛素浓度。这种作用与牛胰多肽注射剂量有明显依从关系,并被预先皮下注射阿托品所部分阻断。结果提示,中枢给予牛胰多肽可能部分通过迷走神经途径增加血清胰岛素的释放而增加糖耐量。
【Abstract】 Glucose tolerance and serum insulin concentration of rabbits were increasedby injecting BPP into the lateral ventricles and showed a marked dose-dependentrelationship.The effects of BPP were partly abolished by injection of atropine.This is probably due to release of insulin brought about through the action of vagusnerves.
【关键词】 牛胰多肽;
侧脑室;
糖耐量;
血清胰岛素;
阿托品;
【Key words】 bovine pancreatic polypeptide(BPP); cerebro-ventricular; glucose tolerance; serum insulin; atropine;
【Key words】 bovine pancreatic polypeptide(BPP); cerebro-ventricular; glucose tolerance; serum insulin; atropine;
- 【文献出处】 生理学报 ,Acta Physiological Sinica , 编辑部邮箱 ,1984年04期
- 【被引频次】6
- 【下载频次】31