【摘要】 利用应变规记录33只急性猫的胃窦部蠕动,同时用双极电极记录其胃电。结果发现,微量注射吗啡(10μg/2μl)于低位延髓背部或电针双侧“足三里”都能引起胃窦部蠕动增强(P<0.01)和部分动物簇状锋电位发放。如果事先向低位延髓背部微量注射纳洛酮(2μg/5μl),则电针“足三里”的增强胃窦部蠕动的效应就不再出现。这些结果提示电针“足三里”引起的胃窦部蠕动增强与脑内阿片样物质释放,及其作用于低位延髓背部的一些神经结构有关。更多还原

【Abstract】 The present study was designed to examine whether the opiate like substances(OLS)in the caudal medulla takes any part in the modulation of stomachcortraction induced by eletroacupuncture of“Zusanli”(a point of the StomachChannel).A strain gauge and a pair of electrodes were sutured to the antrum torecord antral peristalsis and electrogastrogram in 33 cats.A stainless steel needlewith an external diameter of 0.5 mm was inserted into the dorsal part of caudalmedulla for injection of drugs.After an injection of morphine(10μg/2μl),the amplitude of antral peris-taisis was markedly increased.Bursts of spikes were also seen in some animals.lectroacupuncture of“Zusanli”produced similar effects as morphine.The ef-fects of electroacupuncture of“Zusanli”could be reversed by injection of naloxonein the dorsal part of caudal medulla(2μg/5μl):instead of augmentation,peristalsiswas suppressed.Saline injected into the same part of medulla did not cause anyreversal of electroacupunctural action.The results escribed suggest that the electroacupuncture of“Zusanli”releases OLS in certain part of the brain which acts on some neural structures at thedorsal part of caudal medulla oblongata which,in turn,exert a descending influen-ce to modulate antral movement and electrical activities.更多还原