【摘要】 本文报道用差示扫描量热法测定7种青霉素钠盐的热降解稳定性,用Kissinger方程计算反应活化能。这些青霉素类药物的热降解稳定性以下列次序增加:青霉素钠<羧苄青霉素钠<苯唑青霉素钠<氨苄青霉素钠<邻氯青霉素钠<氧哌嗪青霉素钠<磺苄青霉素钠。青霉素钠最不稳定。更多还原

【Abstract】 The thermal stability of seven penicillins was studied by the differential scanning calorimetry technique. The activation energy was calculated from Kissinger equation. The thermal stabilities of penicillins increased in the order: Benzylpenicillin<C Oarbencillin < Oxacillin < Oloxacillin < Ampicillin < Piperacillin < Sulfooillin. Obviously benzylpenicillin was the least stable of the penicillins examined.更多还原