【摘要】 采用吡喹酮治疗102例囊虫病患者。脑型70例,其中68例有皮下结节并存;单纯皮肤肌肉型32例。结果表明:①本品对囊虫皮肤肌肉结节具有良效,治疗后2～34月获得随访的52例中,29例结节完全消退,22例结节明显减少,另1例结节反见增多。②对20例脑型患者治疗后随访2～34月,有癫痫症状的13例中,4例癫痫未再发作,8例癫痫发作减少,1例未愈。其中5例颅脑计算机体层扫描(CT)有相应的改善。3例颅内高压型颅内压均降至正常,4例无症状型中3例情况依然良好;1例出现失语。③37例颅脑CT的阳性表现可分为7种类型。CT对诊断及随访疗效有相当价值。④副作用多为暂时性。作者强调指出脑型患者应住院治疗。更多还原

【Abstract】 One hundred and two oases of oystioercosis proved by biopsy and/or computerized tomography (OT) of brain were treated with praziquantel. Among them 70 oases belonged to cerebral type with coexistence of subcutaneous nodules in 68, and 32 cases . were of simple dermo-muscular type. Treatment with praziquantel showed the following results..1. The drug was very effective for cases with dermo-musoular nodules. Follow-up study of 52 oases for 2 to 34 months after treatment revealed complete disappearance of nodules in 29, a significant reduction of the number of nodules in 22, while there was an increase in one.2. 20 oases of cerebral oystacercosis had been followed-up for a period of 2 to 34 months after treatment. 4 oases showed complete remission of symptoms with OT changes returned to normal in 2. Epileptic seizures decreased in 8 patients with corresponding improvement of OT in 3. The high intraoranial pressure returned to normal in 3 oases. 3 asymptomatic oases were in good condition after treatment. 2 patients showed aggravation of both symptoms and OT changes.3. Brain OT changes in 37 cases could be classified into 7 types. It was found that OT examination was a useful tool for diagnosis and follow-up study of cerebral cystioercosis.4. The adverse reactions of praziquantel were mostly of transient nature. However, it is deemed necessary that patients with cerebral cysticercosis receiving praziquantel should be hospitalized under close observation.更多还原