【摘要】 本文报道了71例急性肾小球肾炎（AGN）血清循环免疫复合物（CIC）及134例肾脏病血清补体（C₃）和免疫球蛋白（Ig）的测定结果。在AGN的初期,血清CIC显著高于正常儿童,C₃显著低于正常儿童。随疾病的恢复,GIC渐降,C₃渐升,两者呈完全性负相关。AGN中CIC显著升高伴C₃显著降低者,病情严重、病程长;血清CIC持续不阴转伴有C₃持续低值者预后不佳。肾病时除IgM偏高外,IgG、IgA均降低。本文提示:（1）AGN的发病机理主要是由IC所致;（2）单纯性肾病与细胞免疫有关;（3）测定血清CIC和C₃均有助于肾脏疾病的鉴别诊断、观察病情及判断预后。更多还原

【Abstract】 This article reported the results of the determination of circulating immune complex （CIC） in 71 cases of acute glomerulonephritis （AGN） and those of serum complement （C₃） and immunoglobulins（Ig） in 134 cases of nephrosis. In the initial stage of AGN the level of CIC was remarkably higher than that of normal children, but C₃ was lower. That is to say, the level of CIC was almost always associated with negative C₃. When CIC was remarkably higher with a notably low level of C₃, the case of AGN was serious,and its course might be comparatively longer when CIC was persistent with a low level of C₃, showing that the prognosis was poor. In nephrosis IgM was slightly higher, but IgG and IgA were all low. The article suggested that: （1） AGN is caused by CIC; （2） Nephrosis is related with cell immunity; （3） The determinations of CIC and C₃ are useful for differential diagnosis, observation of the disease course and prediction of the prognosis of nephrosis.更多还原