【摘要】 <正> 近几十年来,肺癌发病率和死亡率在癌症中不断上升,目前世界上有许多国家肺癌死亡率在癌症构成中已跃居第一位。国内外许多调查结果表明,城市肺癌发病率和死亡率高于农村,市区高于郊区,并认为肺癌死亡率高低与大气污染程度密切相关。近来在深入研究肺癌环境致病因子中,有人用大气飘尘及高速公路、隧道空气污染物进行致突变性试验,结果证明城市空气污染物均具有明显的致突变作用。最近WHO 和联合国环境规划署(UNEP)指出:“除了大气质量与人体健康有关之外,室内空气质量对健康更为密切,因为人们90%以上时间是在室内度过的”。更多还原

【Abstract】 The results of Ames’tests show that nitromethane extracts of the indoor andoutdoor suspended particulate matter have obvious mutation effect on both TA98 andTA100.The reverting effect on TA98 is more obvious than TA100,with s-9 than with-out s-9,indoor than outdoor and in cities than in suburbs.However,the revertingeffect of methanol extracts and cyclohexane extracts of the suspended particulatematter on TA98 or TA100 are not so obvious as the nitromethane extracts.The metha-nol extracts have teratogenic effect on bone marrow cell chromapomes in the mice.Thetest research proves that the mutagens mainly contai pnolycyclic aromatic comsoundsThey have not only the direct mutation effect but also the indirect effect on certain,strains of tested Salmonella.更多还原