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以聚合OT为抗原用酶联免疫吸附试验测定结核病人血清特异抗体的初步研究
PRELIMINARY STUDY ON ELISA WITH POLYMERIZED OLD TUBERCULIN ANTIGEN FOR DETECTION OF SPECIFIC ANTIBODIES IN SERA FROM TUBERCULOSIS PATIENTS
【摘要】 本文报告了以聚合OT为抗原,用ELISA法检测了197名健康人、40名活动性肺结核病人及45名其他疾病患者血清的结核IgG抗体。结果40名活动性肺结核病人36例阳性,阳性率90%;197名健康人8例阳性,阳性率4.06%;45例其他疾病患者2例阳性,阳性率4.4%。结果显示,结核病人与健康人及其他疾病患者之间的阳性率差异有高度显著性(P<0.01)。提示该方法有较高的特异性和敏感性。初步认为,本法可作为普查筛选结核病人和协助诊断结核病的重要手段之一。
【Abstract】 A detection of specific tubercle antibodies in the sera from 40 cases of active pulmonary tuberculosis, 200 healthy controls and 46 patients with other diseases was made by ELISA in polymerized old tuberculin antigen. The ELISA test was positive in 90% of the cases of active pulmonary tuberculosis, 4.34% of the cases of other diseases and 4.5% of the healthy controls. The results show this study is statistically highly significant (P<0.01). It is suggested that the method is highly sensitive to the detecting of specific tubercle antibodies.
- 【文献出处】 湖北医学院学报 , 编辑部邮箱 ,1984年03期
- 【被引频次】3
- 【下载频次】10