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慢性铍病免疫学诊断指标的探讨

A STUDY ON IMMUNOLOGICAL INDEXES FOR DIAGNOSIS OF CHRONIC BERYLLIOSIS

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【作者】 姚剑君胡素英

【Author】 Yao Jianjun (Hunan Institute of Metallurgicical Industrial Hygiene)

【机构】 湖南冶金防护防治研究所湖南冶金防护防治研究所

【摘要】 本文对108名铍接触者与73名未接触过铍的健康对照者进行了五项免疫学观察。其中以铍为抗原的白细胞移动抑制试验,可以早期发现铍致敏的个体和活动型铍病患者,故可作为铍病诊断的辅助指标,并有助于鉴别诊断和判断疗效。作了非特异的细胞免疫试验(淋巴细胞转化率、E-玫瑰花结试验、OT试验),结果表明慢性铍病患者的细胞免疫功能明显降低。

【Abstract】 Five immunological tests had been performed on 108 workers exposed to beryllium and 75 healthy ones as normal controls. It showed that Be-induced leucocyte migration inhibition test (Be-LIT) could find out the patients with activating beryllium disease at earlier stage and the Be-sensitive cases. Thus it could be used for supplementary diagnostic index for berylliosis and might be useful for differential diagnosis and for evaluating the curative effect. The non-specific cellular immunological tests (lymphocyte transformation, E-rosette formation test, OT test) had been done as well. It suggested that the capability of the cell-mediated immunity was significantly diminished in patients with chronic beryllium disease.

  • 【文献出处】 工业卫生与职业病 ,Industrial Health and Occupational Diseases , 编辑部邮箱 ,1984年06期
  • 【被引频次】6
  • 【下载频次】40
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