【摘要】 弯曲菌(Campylobacter)首次由兽医工作者MacFadyean和Stockman于1909年从传染性流产的牛的胎盘和胎儿中分离到,他们称之为胎儿弧菌(Vibriofetus)。其后的研究证实该菌是引起牛,羊流产的主要病原菌之一。1947年Vinzen等报告从一位流产的孕妇血液中分离出胎儿弧菌,以后,偶而有人报道过该菌亦可从血液,脑脊液,关节抽吸物等标本中分离,而且多见于肿瘤、糖尿病、心血管疾病或老年患者,因而认为是一种条件致病菌。并由于该菌形态呈弯曲状而归类在弧菌属,称为相关弧菌(Related vibrios)。直到1972年Dekeyser等在比利时第一次证实胎儿弯曲菌空肠亚种(C.fetus jejuni)简称空肠弯曲菌,是引起小儿和成人急性胃肠炎的常见病原菌以后,才引起了各国研究者重视。近十多年来,该菌的生物学分类,培养特性,血清学分型,致病性以及流行病学特点等均有不少报道。至于空肠弯曲菌与动物腹泻的关系如何,亦日渐为广大兽医工作者所关注,正在进行各方面的深入探讨。 由于工作需要,我们在1983年5—9月,对153例恒河猴(其中53例为腹泻病猴)的粪便标本,进行了空肠弯曲菌的分离鉴定,以便探明该菌在恒河猴腹泻中的病因学地位。现将初步结果报告如下。更多还原

【Abstract】 The isolation and identification of Campylobacter jejuni in feces of 53 rhesus monkeys with diarrhea and in 100 healthy monkeys were made in May to September, 1983. Among them 18 cases were found to be positive in 53 monkeys with diarrhea; its percentage of isolation was 33.9% while 5 cases were positive in the 100 healthy monkeys; its percentage of isolation was 5%. In the meantime, Shigella flexncri was isolated from 13 of 53 monkeys with diarrhea; its percentage of isolation was 24.4%. Both Campylobacter jejuni and Shigella flexneri were isolated from 4 cases of the monkeys with diarrhea (7.5%) (mixed infection). None of the 18 sick animals died after treatment with erythromycin. This preliminary work shows that Campylobacter is significant in the etiology of rhesus monkey’s diarrhea as well as Shigella flexneri.更多还原