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激光血卟啉衍生物治疗体表恶性肿瘤六例报告

A PRELIMINARY STUDY OF HEMATOPORPHYRIN DERIVATIVE PLUS LASER RADIATION FOR THE TREATMENT AND DIAGNOSIS OF SUPERFICIAL WALIGNANT TUMOR

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【作者】 于赤兵孙学俭张家年谈善庆孙弘蔡永镳

【Author】 Yu Chibin, et alDepartment of Surgery, Second Teaching Hospital

【机构】 第二军医大学第二附属医院外科第二军医大学第二附属医院皮肤科第二军医大学第二附属医院口腔科上海医用激光仪器厂

【摘要】 本文报道我院应用激光血卟啉衍生物(HPD)诊活体表恶性肿瘤6例(18个瘤灶)的方法和结果。5例获得了较满意的近期效疗,1例因激光照相时局部疼痛而中止治疗。本组病例按18个瘤灶计算,瘤体完全消失14个,部分消失3个,无反应1个。本法对癌肿组织选择性高,但对癌肿附近近正常组织无明显损伤,在治疗过程中未见有全身反应,而且操作简便、安全,说明本疗法是治疗体表恶性肿瘤一种很有前途的疗法。本文并对激光HPD诊治恶性肿瘤的机理、诊断和治疗用光源等有关问题进行了讨论。

【Abstract】 In this paper we were reported the method and the result of the application of hematoporphyrin derivative(HPD) plus laser radiation for the diagnosis and treatment of superficial malignant tumor for 6 cases (18 focuses).The early effect of this method was rather satisfactory in 5 cases.Due to the pain caused by laser radiation, the treatment was cesed in one case. According to 18 focuses, 14 focuses were completely disappeared, 3 focuses were partially vanished, and no response in one focus.It shows high selectivity to the tumor tissue and without significant trauma in the normal tissues surrounding the focus.During the course of treatment, no general reaction can be seen. It proves that this method may have a prospective future in the treatment of superficial malignant tumor. In this article we have also discussed the mechanism of HPD plus laser radiation for the treatment of malignant tumor and the light source for treatment ana diagnosis etc.

  • 【文献出处】 第二军医大学学报 ,Academic Journal of Second Military Medical University , 编辑部邮箱 ,1984年01期
  • 【被引频次】1
  • 【下载频次】6
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