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关于不可逆性失血性休克大量补液的研究

The Therapeutic Effect of Large Dose Balance Solution Infusion on Irreversible Hemorrhagic Shock

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【摘要】 用大剂量平衡盐溶液静脉输入治疗家兔不可逆失血性休克未见疗效,若同时合并使用654-2则疗效显著增加,而合并使用毒毛旋花子素K及同时合并使用毒毛旋花子素K及654-2均未见疗效。看来654-2治疗休克的机制可能是改善了微循环。

【Abstract】 Large dose of balance solution (BS) insused intravenously alone did not show any therapeutic effect during experimental irreversible hemorrhagic shock (IHS) in rabbits. However, a significant beneficial result appeared when BS and Anisodamine (A) were employed together. Administration of either BS and Strophanthin K (S) or a triad of BS, S and A failed to produce satisfactory result. It seems probably that A may play certain role in the therapeutic effect of IHS via its influence in the improvement of microcirculation.

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