【摘要】 <正> 含有碳—碳双键的不饱和有机化合物直接与氘气反应,特別是在催化剂作用下,容易发生亲电加成反应,标记物的结构和性质都发生变化,达不到标记目的。N_{3,4-氯苯丙烯酰基}-另丁胺是一种新的抗癲痫药物。N-（2-甲基-2-哌啶基-乙基）-N-（2-吡啶基）-丙酰胺富马酸盐（简称异普罗匹拉富马酸盐）是一补作刚较强的镇痛剂,已通过更多还原

【Abstract】 The unsaturated organic compounds N-(2,5,6-~3H-3, 4-dichlorophenyl propenoyl)-isobutyl amide and ~3H-isopropiramfumarate were prepared with their tritiated intermediates by chemical synthesis. The specific activity of the products are 28.2mci/mM and 30.7mci/mM, respectively the radiochemical purity of the products arc over 91.5％. The advantage of chemical synthesis method is that the reaction of unsaturated organic compounds with tritium gas is avoided. This ensures the unsaturated compounds containing carbon-carbon double bonds do not become hydrogenated.更多还原