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从原发性肝癌的家族性分布探讨乙型肝炎与其发病关系

The relationship between HB and liver carcinoma: A study of familial assembly occurrence of primary liver carcinoma

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【作者】 刘玉环郭继玲黄玉璞

【Author】 Liu Yuhttan et al

【机构】 白求恩医科大学第一临床学院传染科双阳县医院内科

【摘要】 <正> 近年来许多研究表明,乙型病毒性肝炎与原发性肝癌关系极为密切,二者呈家族性分布已早有报道。为进一步探讨二者关系,现将我科遇到的吉林省双阳河公社同一家族中弟兄4人同患原发性肝癌的病例,以及对其家庭及密切接触者所做的调查情况报告如下。

【Abstract】 A familial assembly occurrence of primary liver carcinoma is reported in this paper. A patient and his three brothers died of liver carcinoma in seven and a half years.Of the 46 persons who had had close contacts with the patient and his siblings, 21 had hepatomegaly, among whom 7 had anamnestic hepatits; HBsAg was positive in 10 persons (21.7%) , anti-HBc was positive in 13 (38.5%) , HBeAg was positive in 4 (8.7%) ; and abnormality of liver function was found in 5 persons. Evidence presented suggests apparent relationship between HB and liver carcinoma, the principal factor of HB in the occurrence of liver carcinoma, and the assembly occurrence of liver carcinoma in a family. Our results are clear enough to warrant the necessity of controlling HB in the prevention of liver carcinoma.

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