【摘要】 <正> 聚甲基丙烯酸己磺酸钠(PSSHMA)是我们最近合成的,具有较好抗凝血性能的高分子聚电解质。在有盐存在时,聚电解质溶液的比浓粘度与浓度依赖关系发生变化。关于不同盐浓度存在时,聚电解质溶液比浓粘度与浓度的关系,Conway,Markovitz,Hiroshi等曾进行过研究,提出一些经验式。Yeh根据高分子链体积效应的分布函数进行处理,也曾得出在一定外加盐浓度时,特性粘度[η],外加盐浓度C_s,聚合物分子量M三者之间的关联式。在较高盐浓度存在时,更多还原

【Abstract】 We have recently synthesized a new polyelectrolyte with improved anticoagulant activity, the sodium salt of poly-6-sulfohexyl methacrylate (PSSHMA). It has been fractionated into fourteen fractions with different molecular weights. From the experimental data it was not possible to get good straight lines by means of empirical formula reported previously and therefore a more general mathematical model is developed by using statistical method.[nn]=KMα + BCx-β Mγ (1)where α, β, γ, K and B are parameters to be optimized, with α, β and γ>0. And then the Orthogonal aγay is used for choosing the value of α, β and γ. Seven levels for each of the α, β and γ are chosen close to 0.625, 0.5, 0.875 respectively. For complete permutations, it is necessary to compute 73 = 343 times regression planes. Now Orthogonal aγay L49 (78) are used. 49 times which have representatives to match the regression equations are selected. These data are computed by means of FORTRAN language on the CROMEMCO micro computer. Linear coefficients K and B in equation ( 1 ) are calculated around a group data of α, β and γ. Residual sum of squares Q is investigated as the target of the Orthogonal aγay. From forty-nine computations the minimum of Q is obtained and equals to 5139 when α, β and γ equal to 0.55 0.50 and 0.80 respectively. According to the computated results of the first group, we change the value of α, β, γ, and continue to use Orthogonal aγay L49 (78) for seeking the optimum, until the value of Q reduces to 1268. Finally, 125 regression planes have been made, around the better point, when α, β and γ equal to 0.655, 0.025 and 0.655 respectively the value of Q achieves the minimum and equals to 1225. We stopped the optimazation at these values of parameter α, β and γ since they are the best ones in the region we searched. It can be concluded that a better relationship among [nn], M and Cs of aqueous solution of PSSHMA is obtained: according to the equation ( 2 ), we use our experimental data, a much better straight line is obtained.更多还原