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镍钛记忆合金的医学基础研究

STUDIES ON NICKEL-TITANIUM SHAPE MEMORY ALLOY WITH HISTOLOGICAL TEST

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【作者】 薛淼李一鸣顾国珍吕全庚陈希贤俞育飞余前春陈瑞珍泮可风竺涵光泮家琛丁永敏顾基中韩研丽施耀舜

【Author】 Xue Miao, et al ( Shanghai Second Medical College )

【机构】 上海第二医学院上海第二医学院

【摘要】 镍钛汜忆合金在模拟体液介质中有轻度变色现象,但在动物体内埋植后却没有。在大鼠皮下和骨内埋植10个月的实验说明,对局部组织无损害,炎症反应轻,组织修复过程时间短,未见变色、腐蚀和细胞毒性迹象,具有较高的生物相容性和较低的生物退变性。在相当于生物寿命2/5观察期内,未见局部肿瘤产生。与316L不绣纲和碳纤维增强碳相比,镍钛记忆合金是一种较好的生物材料。

【Abstract】 <ABSTRACT>Nitinol, a nickel-titanium alloy with shape memory, was reported and itstissue response investigated.The tissue response test revealed that no evidence of reaction or resorption after implantation ( 60 specimens ) was noticed over a period of 10 mos.Histologically, 1 wk after implantation, the nitinol implant was covered with a layer of spongy matter of newbone. Then the compact bone gradually increased and 8 wks after implantation, normal bone was observed.The authors suggest that nitinol is an ideal implant material in dental and surgical clinics.

  • 【文献出处】 中国生物医学工程学报 ,Chinese Journal of Biomedical Engineering , 编辑部邮箱 ,1983年01期
  • 【被引频次】69
  • 【下载频次】162
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