【摘要】 本文研究酶联免疫吸附试验(ELISA)检测特异性IgG、IgM和IgE在日本血吸虫病诊断和疗效考核中的意义。发现在207例确诊的血吸虫病患者中,ELISA的阳性率为97.6％,65例非血吸虫病患者无1例呈假阳性反应。吡喹酮治疗后6～8个月随访,在117倒粪检阴转者中,ELISA-IgM的阴转率为80.3％。就这点而论,血吸虫病化疗后IgM阴性值可能意味着有效治疗。50例同时进行微量采血法和静脉采血法,其中48例的结果相符,可以说明微量采血法是现场试验选用的一种方法。更多还原

【Abstract】 This article deals with the determination of specific IgG, IgM and IgE to soluble egg antigen in schistosomiasis japonica to assess the therapeutic efficacy of antischistosomal drugs. It was found that 97.6% of the proved cases were positive by ELISA, while all of the sixty-five patients other than schistosomiasis were negative. Follow-up stool examinations of 131 patients for 6-8 months showed that 117 cases (89.3%) turned negative after pyquiton treatment, and 80.3% of the cases also revealed IgM negative. In this context, IgM negatives following chemotherapy of schistosomiasis meant an effective treatment. 48 out of 50 cases showed comparable results after simultaneous capillary and venous blood samples, so capillary method turned out to be one of the choices in field studies.更多还原