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用鲎试验检查感染鼠疫的实验动物内毒素血症
Examination of Endotoxaemia in Experimental Laboratory Animals Infected with Plague by Means of Limulus Test
【摘要】 <正> 对鼠疫菌引起机体损伤和死亡的机理,迄今仍不太清楚,人们在长期的临床观察和研究中,认识到鼠疫的发病和死亡是毒素的作用。近十年来多数学者才倾向性地认为,鼠疫菌存在两种性质上截然不同的毒素,一种为鼠毒素,一种为内毒素。
【Abstract】 The endotoxaemia of the guinea-pig infected with Y. pestis is detected withLimulus test.The result demonstrates that endotoxaemia and its clinical symptomshave been produced in most animals on fifth to sixth days after infection. Theseanimals would be killed, when the endotoxin concentration is reached or exceledin 10 μg/ml. The authors believe relationship between the clinical symptoms andthe death of plague patient with the endotoxin of Y. pestis in the organism.
- 【文献出处】 中国地方病学杂志 ,Chinese Journal of Endemiology , 编辑部邮箱 ,1983年03期
- 【被引频次】2
- 【下载频次】26