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金荞麦有效成分的研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF FAGOPYRUM CYMOSUM (TREV.) MEISN

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【作者】 刘永漋; 房其年; 张秀琴; 冯向新; 张兰芬; 何雪文;

【Author】 LIU Yong-long, FANG Qi-nian, ZHANG Xiu-chin, FENG Xiang-xin, ZHANG Lan-fen and He Xue-wen (Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing)

【机构】 中国医学科学院药物研究所; 南通中药厂; 南通市中医院 北京; 北京; 北京;

【摘要】 <正> 金荞麦(即野荞麦)为蓼科植物Fagopyrum cymosum(Trev.)Meisn,药用其根茎,民间用于治疗肺脓疡。试用于菌痢、麻疹后肺炎等疾患也获得较好的疗效。为了阐明有效成分,我们对其化学成分进行了研究。文献中报道,自多种荞麦中曾分得芦丁和无色花色甙元等成分。 我们从根茎中分得化合物甲、乙和丙三种成分。化合物甲为其主要有效成分,经制备成

【Abstract】 The folk drug of Fagopyrum cymosum (Trev.) Meisn has been reported to have pronounced therapeutic effect in the treatment of pulmonary sepsis. The present paper deals with the elucidation of the active principles of this plant. Three components were isolated. Component A was the main constituent in this drug and accounted for its therapeutic effect. The octamethylether, octamethylether diacetate and decanacetate derivatives were prepared from this component. On the basis of spectroscopic analyses, degradation products and physico-chemical constants, component A was identified as the dimer of 5, 7, 3’, 4’-tetrahydroxyflavan-3-ol(C4-C8 linked), named dimeric procyanidin.Components B and C were identified as heeogenin and β-sitosterol, respectively.

  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1983年07期
  • 【被引频次】60
  • 【下载频次】444
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