【摘要】 <正> 据报道山苍子(Litsea cubeba(LOUR.)pers)油治疗冠心病心纬痛有效,但尚无实验资料证明。此外,已证明游离脂肪酸(FFA)升高在急性心肌梗塞中有重要意义,因此我们对山苍子油保护心肌缺血性损伤及对血FFA的作用进行了初步实验,现将结果简报如下。更多还原

【Abstract】 The possible protective effect of the essential oil of Litsea cubeba (LOUR.) Pers (L. C. oil) on experimental myocardial infarction in rabbits and myocardial necrosis induced by isoprenaline in rats were evaluated. The present study demonstrated that the animals treated with the oil showed improvement of ECG ST segment or "J" point changes and a reduced number of development of new O wave. L. C. oil offered beneficial effect on infarct size as indicated by N-BT staining in rabbits. Furthermore, lowering of serum-free fatty acid concentration of rabbits suggest that L. C. oil had advantageous effect on myocardial metabolism. The precise mechanism involved in tile anti-infarct effect of the oil isbeing studied in our laboratory.更多还原