【摘要】 本文通过透射电子显微镜观察感染日本血吸虫病的小白鼠经硝硫氰胺治疗后,其体内虫体体壁的超微结构的变化。结果表明,硝硫氰胺对血吸虫虫体壁包括表皮,肌层和皮层细胞的超微结构都有程度不等的影响。并且发现表皮内的二种主要包含物,多膜层小泡(M、L、V、)及盘状颗粒(D、G)的减少与消失对表皮的超微病理改变有密切的关系。同时,对血吸虫虫体标本超薄切片的制备方法也进行了探索。更多还原

【Abstract】 The fine structure of the tegument of Schistosoma japonica was studied by means of transmission electron microscopy.Mice infected with schistosomes were treated with nithiocyamine (PEG Form) orally at the dosage of 24 mg/kg/day for three days. The worms that moved to the liver of the animals, 24 hours after this treatment, were studied by means of electron microscopy. The walls of worms including the tegument, muscle layers and tegumental cells were found to be affected. The decrease and disappearance of two major cytoplasmic inclusions in the tegument, multilaminate vesicles and discoic granules of the schietosomes seemed to be related to the pathological changes of its ultrastructure. The damages of the walls of the worms disturbed its’ absorption, metabolism and protective function.Attempts have also been made to study the methods of ultrastructure section of Schistosoma japonica.更多还原