【摘要】 本文对55例出血热患者甲状腺功能进行了动态观察,结果表明出血热患者血清促甲状腺素（TSH）明显高于正常人;总 T₃（TT₃）、总 T₄（TT₄）则不同程度的低于正常,反 T₃（rT₃） 与 TT₃ 呈相反方向的变化,即当 TT₃ 降低时 rT₃上升。上述变化以低血压、少尿期为明显,提示出血热病程中除有强烈的应激反应外,还有低 T₃及/或低 T₄综合征存在。血清 TT₃/rT₃比值的变化能反映病情的轻重。更多还原

【Abstract】 The thyroid hormone levels in 55 patients with epidemic hemorrhagic fever（EHF）were dynamically analysed during the whole course of the disease.The result showed that all patients had increased serum TSH levels at each phase in the course of the disease and the values of serum TSH in the mild group were higher than in those of the severe group. In most cases,the concentration of total serum T₄（TT₄）was significantly decreased（6.2± 3.69μg/dl）at the critical stage of the disease.The mean serum T₃ concentration patients revealed a markedly reduced trend form febrile stage to early convalescent stage,special- ly,it was the lowest in the oliguric stage.The reciprocal change in serum TT₃ and rT₃ levels was observed in hypotensive and oliguric phase. The data obtaind from this study suggested that besides a strong stress,a low serum T₃ and/or T₄ syndrome may be present during the course of the disease in most cases of EHF.The authors recommended that the dynamical analysis of serum TT₃/rT₃ may be helpful to judge the prognosis of patients with EHF.更多还原