【摘要】 <正> 细菌性腹膜炎仍是当今外科需要解决的一个问题。利用动物模型进行疾病的研究已被证明是一个有效的研究方法,但必须首先解决模型问题。本文目的是复制细菌性腹膜炎的动物模型,希望在病理学、细菌学和死亡率等方面都接近人的临床情况。我们复习了各种实验动物(大白鼠、小白鼠、豚鼠、兔更多还原

【Abstract】 The aim of this study is to make an animal model of bacterial peritonitis whichis similar to the disease of human beings Pathologically bacteriologically and inmortality rate.Rats were used.2ml of plasma of rabbit,lml of normal saline,0 to9O×10(?) E.coli,and 10 units of ox thrombin were mixed up,and the clot formed wasimplanted into the abdominal cavity of rats,resulting in localized peritonitis.90×10(?) E.coli,3 to 5ml of normal saline and 0 to 2ml of plasma of rabbit were mixedand injected into the abdominal cavity of rats,resulting in diffuse peritonitis.The results of this study gave us an impression that both models of peritonitis weresimilar to the clinical picture in general,mortality and abdominal pathology(grosslyand microscopically)of human beings.The conditions recquired for model prepara-tion.methods of observation,merits and demerits and the use of the two modelswere discussed.更多还原