【摘要】 本文报道对10例Ⅱ期晚卵巢上皮癌综合治疗的体会。治疗方法为腹壁下动脉插管化疗,疗程次数视病情需要而定。化疗后在腹水消退、痞块缩小的基础上施行手术。术后再加用腹腔化疗、放射治疗和静脉化疗2年。经上述综合治疗后有6例存活2年以上,其中2例已存活3年左右。本文认为卵巢上皮癌较晚期患者,尤其并发腹水者以先给动脉化疗为宜,待腹水消退、病灶缩小后,再行剖腹手术。对术前未经化疗而手术者,发现不能彻底手术治疗者,宁可暂不手术,改给动脉化疗,等待有利时机再行手术及综合治疗。更多还原

【Abstract】 The therapeutic measures began with arterial chemotherapy via inferior epigastric artery catheterization. Each course consisted of daily nitrogen mustard (10 mg) plus actinomycin K (400 μg) on 3 consecutive days followed by 5-FU 500 nag daily for one week after an interval of 3 days. This regimen might be repeated if necessary at 3-week intervals. Operation was performed after subsidence of ascites and regression of the tumor mass, Postoperative intraabdominal chemotherapy, external irradiation and a 2-year course intravenous chemotherapy were then carried on successively. Of the ten cases so treated, 6 cases lived more than 2 years, 2 of them having been alive around 3 years. It is proposed that advanced epithelial cancer of the ovary be treated in this order.For the patients without preoperative chemotherapy, if, upon laparotomy, a thorough operation is found impossible, it is preferable to conclude the operation and give intraarterial chemotherapy instead, followed by definitive resection at a later date.更多还原