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SNPH—骨水泥的研制和临床应用

EXPERIMENTAL STUDY AND CLINICAL APPLICATION OF SNPH-BONE CEMENT

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【摘要】 SNPH-骨水泥是以甲基丙烯酸甲酯为主体,选用2,6—二叔丁基对甲苯酚代替常用的对苯二酚作为稳定剂,以二氧化锆代替硫酸钡作为阻光剂,因而使用更为安全,且能在X线片上满意显彩。经机械性能测试、细菌学检验、动物实验和临床观察,证实其性能良好。骨水泥由于扩大了假体与受体骨间的载荷面和发挥机械性嵌锁作用,故具有防止假体下沉或松动的作用。此外,骨水泥尚可用于充填骨缺损、加固内固定或脊柱侧凸矫正棒和作为第一,二掌骨间支撑物,以及用于掌指关节成形术作为间隔物,方法简便,效果较好。文内还讨论了骨水泥的力学作用和骨水泥植入综合征的防治。

【Abstract】 SNPH-bone cement is composed of methyl-methacrylate, 2, 6-ditert-butyl-p-cresol (instead of hydroquinone as stabilizer) and zirconium dioxide (instead of barium sulfate). Study on mechanical strength of the cement, bacterial culture, animal experiment in 24 rabbits and clinical application in 86 cases all demonstrated the reliability of the SNPH-bone cement. The bone cement can prevent settling and loosening prosthesis by increasing the contact area of the prosthesis bone interface, packing bone defect, reinforce internal fixation or Harrington instruments and serve as a fixation support between the 1st and 2nd metacarpal bones. Besides, the bone cement has been used in metacarpophalangeal arthroplasty as a convenient and effective spacer. The authors are of the opinion that the bone cement is safe and sound as an implant and ensures better visualization in X-ray picture.

  • 【文献出处】 上海医学 ,Shanghai Medical Journal , 编辑部邮箱 ,1983年03期
  • 【被引频次】5
  • 【下载频次】58
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