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电刺激兔隔区对大脑皮层牙髓诱发电位的抑制效应及其同纳洛酮与针剌效应的关系
INHIBITORY EFFECT OF SEPTAL STIMULATION ONCORTICAL POTENTIALS EVOKED BY TOOTHPULP STIMULATION IN RABBITS AND ITSRELATIONSHIP WITH NALOXONE ANDACUPUNCTURE ANALGESIA
【摘要】 弱电流刺激兔隔区明显地抑制大脑皮层诱发电位,而且外侧隔核的作用较内侧隔核显著。刺激隔区的抑制作用可被静脉注射纳洛酮(0.4mg/kg)所对抗,而被电针穴位所加强。由此提示,阿片受体参与电刺激隔区的抑制作用,电针穴位能激活隔区而加强其效应。
【Abstract】 An experiment was carried out on rabbits anesthetized with urethane and ohlora-lose. Cortical potentials evoked by stimulation of the oontralateral tooth pulp were recorded from the ventral portion of the coronal gyrus.When the septal area was stimulated with weak stimulus intensity, the evoked potentials were markedly depressed, manifesting a decrease in the amplitude of the primary response. The effective points for inhibition were located mainly in the lateral septal region. Intravenous injection of 0.4mg/kg of naloxone was able to reverse the inhibition of septal stimulation on evoked potentials in various degrees. The reversal reached a maximum at the 9th minute after injection.In some cases, acupuncture is able to enhance the inhibitory action of septal stimulation.The results imply that (1) brain endorphins are involved in the inhibition of septal stimulation, (2) the afferent impulses arising from the acupuncture points can reach the septal area to excite its activity.
- 【文献出处】 上海第一医学院学报 , 编辑部邮箱 ,1983年06期
- 【被引频次】1
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