【摘要】 1.1975年于内蒙自治区蒙族牧民中发现一种D型β链异常血红蛋白,暂命名为血红蛋白D-乌兰花。2.本文对此变异物做进一步分析,弄清其一级结构特点为β121谷→谷胺,证明Hb D乌兰花=Hb D Los Angeles(Hb D Punjab)。3.Hb D Los Angeles在伊朗及印度次大陆的发生率相当高。H.Lehmann曾提出这种血红蛋白可能来源于蒙古族。4,现在我们证明在蒙族中确有Hb D Los Angeles,从而给Lehmann设想的可能性提供了依据。更多还原

【Abstract】 1. In 1975, a D-type hemoglobin with abnormal β-chain was discovered among Mongolian herdsman living in Inner Monggol Autonomous Region. It was named tentatively as hemoglobin D Wulanhua (Acta Genetica Sinica, 1978, 5, 263.) 2. The primary structure showed that this variant was β121 Glu→Gln, demonstrating Hb D Wulanhua to be identical with Hb D Los Angeles (Hb D Punjab). 3. The incidence of Hb D Los Angeles was fairly high in Iran and the Indian sub-continent. H. Lehmann has suggested that it may originate from Mongolian nationality. 4. We have now demonstrated the occurrence of Hb D Los Angeles in Mongolianherdsman, providing presumptive evidence for Lehmann’s assumption.更多还原