【摘要】 <正> pppA2’p5’A2’p5’A（简称2’-5’P₃A₃）是干扰素作用于细胞后诱导产生的物质。干扰素的作用机理很复杂,其中之一是2’-5’寡聚腺苷酸合成酶的活力增加,此酶以ATP为底物合成2’-5’P₃A₃及其同系物2’-5’P₃An。但2’-5’P₃A₃或2’-5’P₃A_n本身是否具有抗病毒作用,干扰素的抗病毒作用是否通过2’-5’P₃A₃或2’-5’P₃An而进行,这是一个很更多还原

【Abstract】 There are contradictions in the literature regarding the antiviral action of 2’-5’oligoadenylate （2’-5’PsAa etc.）. The authors have first reported the protective effectof 2’-5’P₃A₃ on VSV infected cells. In this article it is shown that the antiviralaction of 2’-5’P₃A₃ covered a wide spectrum of viruses, including RNAviruses, suchas Influenza H₃N₂/77, Influenza H₁N₁/77, ECHO₁₁, rhino, Sindbis Sendai, and DNAviruses such as herpes simplex, suggesting the generality of the antiviral actionof 2’-5’P₃A₃.更多还原