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类风湿性关节炎滑膜再生的组织学观察
Study on Histo-Morphological Changes of the Synovial Membrane Regeneration in Rheumatoid Arthritis
【摘要】 本文通过13例不同时间类风湿性关节炎患者滑膜全切除术后所取标本的组织学观察,发现术后一个月再生滑膜已形成;能完全再生;临床分级早者再生尤完好,功能改善也佳。机械因素影响小,感染因素可延缓生长。
【Abstract】 The regenerated synovial membranes of 13 rheumatoid patients who had had previous operations for synovectomy (2 cases) or artificial arthro-displacement (11 cases) were studied. The histological samples were obtained from one to 55 months following the operation respectively. HE stain was used as the main staining, other staining methods including elastic tissue stain, PAS, phosphotungstic acid hematoxylin and Van Gieson stains.The results showed: 1. After the total excision of the synovial membrane, regenerated synovial cells appeared in the form of proliferation and metaplasia of the mesenchymal cells within the connective tissue. 2. The proliferative synovial cell layer was formed in the first postoperative month, the longer the time was, the more mature the layer would be, which was similar to that seen in normalsynovial membrane. 3. Synovial membrane in early stage underwent a complete regeneration. Mechanical irritation did not seem to cause remarkable influence over the regenerated cell layer In case of infection, the course of regeneration was impaired or prolonged.
- 【文献出处】 上海第二医学院学报 ,Acta Universitatis Medicinalis Secondae Shanghai , 编辑部邮箱 ,1983年01期
- 【被引频次】1
- 【下载频次】32