【摘要】 本试验用鼠伤寒沙门氏菌组氨酸缺陷型——哺乳动物肝微粒体酶测试系统(Amer’Test),对正烷酵母饵料浸出液的非极性树脂 XAD-2 吸附物进行检测,以查明其是否具有致突变或致癌作用。结果表明,正烷酵母对菌株 TA98及 TA100有致突变作用,由此证明这种饵料中存在着引起 DNA 移码突变和碱基对置换突变的化合物,故这种酵母在被用作鱼类饵料或其他动物饲料之前,还应作进一步研究,防止其对环境的污染和其他潜在的危害性。更多还原

【Abstract】 Materials in the experiments were prepared by absorbing the extracts of fish foodN-Paraffin yeast. They were tested for mutagenic properties by using the Salmonella Typhimurium/microsomal test system. Mutagenic activity was detected in the preparedN-Paraffin yeast materials. It reveals that this fish food may contain the compound offlameshift and base-pair substitution mutagens. It required metabolic activations. Therefore great care should be taken in using this yeast as the food of fish or otheranimals in order to avoid the potential harmfulness.更多还原