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人扁桃体细胞和外周血白细胞的干扰素产生反应的比较

INTERFERONS PRODUCTION BY HUMAN TONSILLAR CELLS COMPARED WITH PERIPHERAL BLOOD LEUCOCYTES WITH 7 INDUCERS

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【摘要】 本文观察了人扁桃体细胞在体外条件下对植物血凝素(PHA)等诱生剂的γ干扰素产生反应,以及对新城鸡瘟病毒(NDV)等的α干扰素产生反应,并且将扁桃体细胞对这些诱生剂的干扰素产生反应与外周血白细胞的反应进行了比较。

【Abstract】 The interferons(IFNs)-producing ability oftonsillar cells and that of peripheral blood leucocy-tes(PBLs)were compared under the same con-ditions with 7 kinds of inducers(NDV,Staphy.CowI,C.Parum,ConA,SEA,PHA,PWM).Both cells were almost equally potent in produc-ing IFNa with NDV and Staphy.CowI as wellas IFNSr with PHA, PWM and ConA.As tothe IFNs-producing ability with SEA and C.Parum,tonsillar cells are significantly weakerthan PBLs.This difference was discussed withspecial reference to the distribution of lymphocyte-subsets in tonsils and blood.

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