【摘要】 <正> 用天然锑为靶材料,由氢氟酸体系电镀成均匀、牢固、导热性好的靶子,在适当的α粒子能量和靶子厚度下产生医用核纯度的¹²³I,并首先应用一种高效、快速、简便的干法分离流程直接从轰击后的锑靶制备高纯放射性Na¹²³I注射液,整个流程在1小时内完成。总的放射化学产率在98％以上,¹²³I核素纯度大于98.5％(（124）I～0.95％¹²⁶～0.18％),放化纯度（I^-）大于98％,化学杂质Sb、Cu等均小于1ppm。厚靶产额0.30mCi/μA·h。此法制成的产品经过临床前药理试验、临床试用和有机放射性药物的合成,表明质量良好。更多还原

【Abstract】 This paper describes a new process for the production of Na 123I radiopharmaceutical through 121Sb (a, 2n) 113I reaction. Target of natural antimony was electroplated in a HF bath on a silver-copper complex plate. The antinomy layer thus obtained was firmly bound and evenly distributed with definite thickness and good thermal conductivity. The targets were irradiated by a particles of - 30MeV to produce 123I which transformed directly into pure Na123I radiopharmaceutical through a quick dry process of high efficiency. The total time of processing was within an hour. The overall radiochemical yield was over 98% with radionuclidic purity over 98.5%, radiochemical purity over 98%, chemical impurities of Cu and Sb all less than 1ppm. The thick target yield was around 0.3mCi/μAh. The product proved good in preclinical tests for injection, in-vivo uses and labelling of organic radiopharmaceuticals.更多还原