【摘要】 <正> 一、酶促反应中的活化能非酶催化反应与酶催化反应,可以简单地利用下面所谓"热力学箱"反应式来示意: 其中A,B是两种底物,E为酶。(AB)~+是在H.Eyring意义下的过渡状态。K_s,,K_K是相应反应的速度常数。假定反应是在某种溶液中进行的。反应式的第一行表示非酶催化反应,第二行表示首先形成酶一底物复合物EAB,接着通过状态E(AB)~+,最后以一个新的速度常数K_E发生反应到达终态E_+产物。这就是酶催化反应。两种反应途径所到达的终态相同,但是反应的活化能△F不同。如图1。更多还原

【Abstract】 Using Toda’s non-linear lattice theory, the activation energy of the enzyme-catalysed reaction has been studied. A physical mechanism has been obtained fronu the result. From this mechanism, the energy of the stochastic collisions between the molecules in solution and the enzyme can be concentrated to the active site of the enzyme. This activation energy is necessary to form an enzyme-transition complex after an enzyme has combined with substrates.更多还原