【摘要】 本文采用聚乙二醇沉淀-补体消耗法测定了92例不同类型肾小球疾病患儿的循环免疫复合物(CIC)。在各类肾小球疾病中急性感染后肾炎(APGN)患儿的CIC阳性率(27/34)及血清水平均最高,且与APGN的疾病活动性有关。13例患上呼吸道感染的患儿(无肾小球疾病)中4例CIC阳性。APGN患儿的CIC持续时间明显长于上呼吸道感染患儿。12例患儿做了肾穿刺活检,其中7例肾小球证明有免疫复合物沉积的病例中4例CIC阳性,而5例肾小球无免疫复合物沉积的病例中仅1例CIC阳性。更多还原

【Abstract】 CICs were determined in 92 children with glomerular diseases by PEG precipitation-complement consumption (PEG-CC) test. The frequency (27 out of 34) as well as the serum level of CIC in APGN was found to be the highest among various glomerular diseases and was paralleled to the activity of the disease. Out of 13 children with upper respiratory infection (URI without glomerular disease) 4 proved to be CIC positive. The CIC lasted longer in patients with APGN than that of URI. The renal biopses were performed in 12 patients with glomerular diseases. CICs were detected in 4 out of 7 patients who had evidence of deposition of immune complex in glomerulus. On other hand, in 5 patients without the evindenee of deposition of immune complex only 1 patient proved to be CIC positive.更多还原