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从低分化鼻咽癌病人建立鼻咽癌上皮细胞株

An Epithelsal Cell Line Established from poorly Differentiated Nasopharyngeal Carcinoma

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【作者】 谷淑燕赵文平曾毅唐慰平赵明伦邓惠华李昆

【Author】 Gu Shu Yan Tang Wei Ping Zeng Yi Zhao Ming Lun Zhao E Wen Ping Deng Wei Hua Li KunInstitute of Virology, Chinese Academy of Medical Sciences Department of Cancer Research, Zhan Jiang Medical College, Guangdong Institute of Basic Medical Science. Chinese Academy of Medical Sciences

【机构】 中国医科院病毒研究所湛江医学院肿瘤研究室中国医科院基础医学研究所

【摘要】 从一例诊断为低分化鼻咽癌病人的鼻咽部肿物活检组织建立了鼻咽癌上皮细胞株(CNE-2)。初步研究了细胞株的生物学特性和与EB病毒的关系。在病人鼻咽脱落细胞和CNE-2早代细胞中检查出EBNA,但多次传代后EBNA却转为阴性,其原因尚待进一步研究。

【Abstract】 An epithelial cell line, designated as CNE-2, was established from biopsy of a poorly idiff-erentiated nasopharyngeal carcinoma. A primary investigation on the diological characteristics and the relation to Epstein-Barr virus was performed. EBNA was detected in the cast-off cells from the tumor add cells of the third passage and in vitro, but disappeared after several passages. The detailed biological studies are being carried.

  • 【文献出处】 癌症 ,Chinese Journal of Cancer , 编辑部邮箱 ,1983年02期
  • 【被引频次】85
  • 【下载频次】302
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