【摘要】 <正> 本文收集了胃癌及消化性溃疡手术标本共68例,分别测定其病变组织、病变周围胃壁组织及病人全血中铜、锌、镍、钴、铬、镉、锰、铁、镁九种微量元素的含量,并进行了分析比较,初步探讨胃癌组织病理变化与微量元素含量的关系。更多还原

【Abstract】 By using atomic absorption and photometer techniques, the whole blood and serum trace elements (Cu, Zn, Ni, Co, Cr, Cd, Mg, Fe and Mn) in gastric tissue specimensfrom 34 patients with gastric cancer and 34 patients with peptic ulcer were analysed. Theresults were as follows: 1, In comparing the two groups, the Cu level is higher and the Zn level is slightlylower in the whole blood,and hence the Cu/Zn ratio is elevated in the gastric cancer groupthan in the peptic ulcer group. The differences are even more significant in the serum,as well as in the gastric cancer patients with lymphatic metastases. 2, The Zn and Mn contents in gastric cancer tissue are lower than those of pepticulcer tissue and are even lower than those of surrounding normal gastric tissues. There isa tendency of reduction of Zn and Mn contents in the order of following sequence: sur-rounding gastric tissue>peptic ulcer>dysplasia>well-differentiated adenocarcinoma>undifferentiated carcinoma>mucinous carcinoma of stomach. 3, The Ni, Fe, Co levels in whole blood of gastric cancer patients are higher than those of normal individuals. The relation between the changes of these trace elements and pathological changes ofgastric epithelium is discussed.更多还原