【摘要】 <正> 原发性肺癌继发脑转移的发生率颇高,据尸检报告为17～38％。一般认为发生率与细胞类型有关。我院自1973～1979年经病理证实的原发性肺癌164例中,发生脑转移者有18例,占11％。现就原发性肺癌的脑转移发生率与细胞类型的关系,治疗方式与预后的关系作一探讨。更多还原

【Abstract】 In a group of 164 patients of histologically proven P. P. C. admitted between 1973～ 1979, 18 cases were found with brain metastasis. Among the 164 cases, 135 were males, 29 were females with a ratio of 4.7: 1. Thosewith brain metastasis, 14 were males, 4 were females, with a ratio of 3.5: 1. Of 164 cases of P. P. C. 55 cases (36.7%) were squamous cell, 51 cases (34%) wereadenocarcinoma, 44 cases (29.3%) belonged to small eell undifferentiated carcinoma and14 cases were unclassified. Among the 18 cases of brain metastasis, 10 cases (55.5%) wereadenocarcinoma, 5(27.8%) were small cell carcinoma and 3 (16.7%) were squamous. The duration between the time of disgnosis of P. P. C. and the appearance of brainmetastasis averages 7.8 months (median time of 7 months). That with the small cell carcinoma was the earliest (median time of 4 months), adenocarcinoma 6.5 months, squ-amous 16 months. Patients with resection of the involved lung had brain metastasis avera-gely after 11.6 months. Removal of the brain metastastic focus was an ideal procedure. We suggest that in advanced cases, an attempt should be made to adopt various appro-priate treatment in order to prolong the life.更多还原