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广东省四会县11年鼻咽癌流行病学初步分析

Preliminary Analysis of Nasopharyngeal Carcinoma (NPC) Epidemiological Data in Sihui County; Guangdong Province for 11 Years (1970-1880 inclusively)

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【作者】 李景廉张振农凌启南潘启超

【Author】 Li Jinglian Zhang Zhennong Ling Qinan (Cancer Institute of Sihui county)Pan Qichao (Cancer Institute, Zhong Shan Medical College)

【机构】 四会县肿瘤研究所中山医学院肿瘤研究所

【摘要】 <正>四会县位于广东省绥江下游,为中国南方鼻咽癌高发区之一。本文收集了四会县1970~1980年鼻咽癌的死亡和发病资料,并作了初步分析。 资料来源 死亡资料来源 得自1973年和1977年两次死因回顾调查和近几年的死因登记报告,对有关病例,复查中山医学院肿瘤医院等的门诊档案,按姓名逐一复核,弃去重报、误报,并作

【Abstract】 Sihui county is situated in the lower reaches of the Xu River in Guangdong province. It is a NPC high risk area in South China. In 11 years ( 1970-1980 ) a total of 530 deaths due to NPC were recorded, with the average crude mortalityr ate 16.15/105 and standardized (adjusted by Chinese census data in 1964) mortality rate 15.10. The crude mortality rates for each year from 1970 to 1980 were 19.23, 15.9-1, 19.22, 16.11, 14.21,16.49,14.66, 14.18, 14.45 and 17.21, sequentially. The average crude mortality rate for males was 21.79, standardized-22.33; and for females was 10.79, standardized-10.88. The sex ratio of mortalities was 2.02:1. NPC deaths ranked the first among all malignancies every year. The youngest death age of NPC was 15 and the eldest 90. Mortality rate rose steeply after the age of 30 and reached the peak in the 50-59 age group. Crude NPC mortality rates of this county were 2.35 and 2.52 times the mean values of Guangdong province for males and females, respectively.In the 10 years (1971-1980) the incidence of 553 NPC cases was recorded. The crude incidence rate was 18.43, standardized-18.11. The crude incidence rates of each year from 1971 to 1980 were 18.43, 19.83, 21.48, 18.98, 18.07, 22.21, 17.27, 19.66, 17.02 and 13.71, sequentially. The average crude incidence rale for males was 25.12, standardized-26.77; and for females 12.11, standardized-10.93, The sex ratio of incidences was 2.07:1.NPC incidence rose steeply also after the age of 30,and reached the peak in 50-59 age group, but for males only, the peak appeared earlier in the 40-49 year group.The NPC incidence and mortality rates of each year in the period of this 11 years flutuated minimally.In this county, NPC mortality and incidence rates for people speaking the Cantonese dialect (15.82 and 18.29, respectively) and for people speaking the Hakka dialect (16.82 and 18.58) were very similar.It appeared that, there is a higher NPC risk area on the coast of Lungjiang River in the central part of Sihui county. The NPC incidence rate-23.48 (reliable limit: 19.47-27.80) and mortality rate-21.39 (17.90-25.34) of the valley (A) area were higher than those of the surrounding (B) area: 15.19 (12.49-18.29) and 13.43 (10.99-16.23), respectively. The differences were very significant statistically (P<0.001).

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