【摘要】 <正> 实验性过敏性脑脊髓炎是一种有效的筛选免疫抑制药的动物模型,这一模型与人的某些免疫性疾病非常类似。 据文献记述,该实验模型在大鼠、豚鼠等多种动物身上均可进行复制。我们利用豚鼠观察了郁金中钙流拮抗成分—二乙二酸二钾镁水合物和水浸醇提物对该种模型的效果。 (一)实验模型制备方法更多还原

【Abstract】 This paper describes the production of an experimental allergic encephalomyelitis in the guinea pig. The experimental animals Were given intradermally the rabbit spinal cord emuision-complete Freund adjuvent into the pads of both hind feet. 60～80% of the guinea pigs developed paralysis of both hind legs after an incubation period of 14～21 days. Whenthe experimental animals Were injected intramuscularly a preparation extracted with alcohol from the hot Water infusion of Yu-Jin, both the incidence and the morbidity of the allergic encephalomyelitis of the guinea pigs decreased by about one half.更多还原