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筛选镇咳药致咳装置的改进
A MODIFICATION OF THE APPARATUS FOR SCREENING ANTITUSSIVE AGENTS
【摘要】 <正> 研究镇咳药物的实验方法很多,但适用于筛选镇咳药物的方法不多。我国医药科学工作者在研究防治慢性气管炎药物工作中,采用一些简便方,筛选镇咳中草药。在这些方法中,以氢氧化铵气雾法应用较为普遍。此法具有简便易行、效率高、容易掌握等优点。我们用此法进行实验时,发现氢氧化铵气雾对实验者呼吸道亦有刺激作用。为解决这一问题,我们改进了实验装置,将氢氧化铵喷雾装置改为氨气吸入装置。
【Abstract】 A modification of the screening apparatus for evaluating the actions of antitussive agents in mice was reported in the present paper. The principal modification is to change the aerosol of ammonium hydroxide into the inhalation of ammonium vapor. A suction was attached to the apparatus instead of an air compresser, so the glass aerosol device was omitted. In addition to the advantages of the original method, the modified apparatus has the following properties: (a) higher availability for materials and appliances; (b) simplification of equipment; (c) convenience to operate; (d) easy control of conditions; and (e) harmlessness to experimenter’s health.
【Key words】 screening of antitussive agents; inhalation of ammonium vapor; codeine.;
- 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1982年01期
- 【被引频次】4
- 【下载频次】53