【摘要】 从香茶菜属植物香茶菜Rabdosia amethystoides(Benth) Hara中分得七种成分,其中之一香茶菜甲素为一新的四环二萜,有抗实验肿瘤及抑制金黄色葡萄球菌作用。用光谱法配合衍生物制备,确定甲素为7α,14β=羟基-20 α羟甲基-16-贝壳杉烯-11,15=酮乙素为乌苏酸,丙素为β-谷甾醇,己素为硬脂酸,其余成分尚在研究中。更多还原

【Abstract】 From the Chinese drug Rabdosia amethystoides seven components were isolated, one of them is a new four ring diterpenoid to which the name Amethystoidin A is suggested. Its formula was found to be C₂₀H₂₈O₅, m. p. 260～262.5℃. By means of spectral methods combined with chemical analysis the chemical structure of Amethystoidin A was determined tobe ent-7α, 14β-dihydroxy-20 α-hydroxymethyl-kaur-16-en-11, 15-dione。This compound was shown to have inhibitory action on experimental tumor in vivo and heptoma cells and staphylococcus aureus in vitro. The other components "B", "C" and "F" were identified to be ursolic acid, β-sitosterol and stearic acid respectively. The identification of other components is in progress.更多还原