【摘要】 <正> 毛萼香茶菜〔Rabdosia eriocalyx(Dunn)Hara〕系唇形科香茶菜属植物,产云南,四川西部,贵州南部,广西西部;生于山坡阳处灌丛中,海拔750—2600米,俗名大马鞭梢,烂脚丫巴草。民间用叶茎煨服退热,叶治香港脚,根止泻止痢,其成份研究尚未见报道。为了寻找新的抗癌活性成份,我们从其叶的乙醚提取物中分到四个单体,定名为毛萼甲、乙、丙和丁素(eriocalyxin A,B,C and D),根据光谱和化学证据,毛萼甲素和乙素这两个新二萜成份的结构分别确定为Ⅰ式和Ⅱ式。更多还原

【Abstract】 Four componts, eriocalyxin A, B, C and D, were isolated from the ether extract of the leaves of Rabdosia eriocalyx (Dunn) Hara collected in Yunnan. Two of them, namely (Ⅰ) and ( Ⅱ ), were established as new diterpenoids having a spirosecokaurene and an cntkaurcne-skcleton by means of spectroscopic and chemical methods, respectively,Eriocalyxin B possesses in vivo tumor-inhibitory activity.更多还原