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流行性出血热血清流行病学的研究——(二)不同人群EHF免疫荧光抗体的检测

Seroepidemiolgical studies on epidemic hemorrohagic fever (EHF), (Ⅱ) The detection of immunofluores- cent antibody of EHF in various populations.

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【摘要】 本文报导了用黑线姬鼠和褐家鼠鼠肺抗原检验流行性出血热病后血清抗体图象的结果。指出,本病病后一般在第七病日即可检出血清荧光抗体。在第7病日到第41病日的28名患者中,其血清荧光抗体滴度都在1:8O以上,其中15例达1:1280以上。值得注意的是,在65例以前患过EHF的病人中,有35例发现特异荧光,其中有两人是196O年的患者,但其抗体滴度低于1:320。证明某些患者,其血清抗体可持续存在23年之久。

【Abstract】 This papers reported that lung antigens of Apodemus agrarius and Rattus norvigicus had been used for detection of the pattern of antibody response after infected with EHF. The results showed that the fluorescent antibody of patients can be detected usually on 7th day. the titer of antibody reached 1 : 80 totally, 28 sera samples from EHF patients of 7th to 41th days were given all positive immunofluorescent(≥1:80. The titer of antibody in 15 sera samples of them were reaching 1:1280 or more. 35 sera of 65 previous EHF patients were given positive immunofluorescent. Two sera samples obtained from patients who were infected in 1960 were given titers of antibody less than 1:320. Therefore, it suggested that the immunofluorescent antibody following EHF finfected may persists for 23 years.

  • 【文献出处】 安徽医学院学报 ,Acta Universitatis Medicinalis Anhui , 编辑部邮箱 ,1982年04期
  • 【被引频次】3
  • 【下载频次】9
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