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深低温冻存后异体关节软骨移植的实验研究

HOMOTRANSPLANTATION OF ARTICULAR CARTILAGE WITH OSTEOCHONDRAL GRAFTS PRESERVED IN LIQUID NITROGEN IN RABBITS

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【作者】 田小明曲绵域田得祥李梅君林宗智宋卫民刘鼎新

【Author】 Tian Xiaoming;Qu Mianyu;Tian Dexiang, et al Institute of Sports Medicine, Beijing Medical College

【机构】 北京医学院运动医学研究所北京医学院同位素研究室 技术协助技术协助

【摘要】 <正> 关节软骨损伤是常见的运动创伤之一,严重地影响着运动成绩的提高。例如:急性软骨和骨软骨骨折、慢性劳损等。由于关节软骨的再生能力很低,因此损伤后难以恢复。当软骨损伤较浅时,所形成的缺损会长期存留;只有

【Abstract】 Osteochondral grafts taken from 4-week old rabbits and preserved in fliquid nittogen for 4 weeks weretransplanted to the femoral articular cartilages in the knee joints of 34 mature rabbits. The viability of car-tilage grafts were examined by autoradiography (3~H-TDR ) before transplantation. The special method andmedium for the storage of the viable cartilage pieces was proved to be reliable. Studies were performed bylight microscopy, scanning and transmission electron microscopy at various intervals up to 18 months afteroperation. The cartilage grafts survived in the hosts, and there was no morphological evidence of immunerejection. This satisfactory result suggests a hopeful way to repair the injury of articular cartilage forathletes.

  • 【文献出处】 中国运动医学杂志 ,Chinese Journal of Sports Medicine , 编辑部邮箱 ,1982年02期
  • 【被引频次】1
  • 【下载频次】22
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