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试验猪大肠杆菌肠毒血症的病理发生

A STUDY ON THE PATHOGENESIS OF EXPERIMENTAL ESCHERICHIA COLI ENTEROTOXAEMIA OF SWINE

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【作者】 吴时友

【Author】 Wu Shi-you (Institute of Animal Husbandry and Veterinary Medicine Shandong Academy of Agricultural Sciences

【机构】 山东省农科院畜牧兽医研究所

【摘要】 溶血性大肠杆菌O139冻融裂解物离心上清液,通过交链葡聚糖凝胶层析,分离成三大组份。取第一组份,给猪作静脉注射,引起猪内毒素休克的临床症状和病理学变化;第二组份中的一部分给猪作静脉注射,引起猪产生类似于水肿病自然病例的临床症状和病理变化。试验猪大肠杆菌肠毒血症可分为两个类型:由内毒素引起的“内毒素休克型”和水肿病因子引起的“水肿型”(即水肿病)。

【Abstract】 Freeze-thawed lysates of hemolytic Escherichia coli O139 were centrifuged.The supernatant was separated into three portions by Dextran gel (sephadex G-200) chromatography. The first portion was parenterally administered to 7 weaned pigs. The clinical signs and pathology of the inoculated pigs were similar to those found in other endotoxin shocks. The second portion was parenterally administered to 8 weand pigs. Their clinical signs and pathological pictures were the same as those of the naturally occurring oedema disease of pigs. Experimental E.coli enterotoxaemia of swine can be divided into two categories: one is the "endotoxin shock type" produced by the endotoxin and the other "oedema type" caused by oedema diseasa principle.

  • 【文献出处】 畜牧兽医学报 ,Chinese Journal of Animal and Veterinary Sciences , 编辑部邮箱 ,1982年03期
  • 【被引频次】5
  • 【下载频次】39
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