【摘要】 从轻型出血热疫区的褐家鼠肺组织,用非疫区黑线姬鼠和E-6细胞同时分离到与EHF相关的轻型出血热的病原因子,进一步证实褐家鼠为轻型出血热病原的一种重要宿主动物。并证明E-6细胞可用来直接从轻型出血热原始标本分离病毒,为该病病原学诊断、流行病学调查提供了一个简便而又比较安全的试验手段。更多还原

【Abstract】 EHF-related agent of the mild type of hemorrhagic fever was isolated from Rattus norvegicus captured from patients, home in endemic area. This study demon strated further that R. norvegicus is its im portant reservoir host. It was also shown that E-6 cells can be used for direct isolation of the etiologic agent of the disease from rodent specimens, possibly also for the direct isolation of EHF virus. This technique will provide a simple and much safer laboratory tool for the etiologic diagnosis and seroepidemiologic studies.更多还原