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小儿轮状病毒肠炎的临床象及病原学观察

Observation on Etiologic and Clinical Features of Rotavirus Gastroenteritis in Infants and Children

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【摘要】 <正> 轮状病毒已公认为引起婴幼儿秋季腹泻的病原。国内庞其方等首先报导了北京地区轮状病毒肠炎。为了明确天津地区秋季腹泻的病原及临床象,我们于1981年9月25日至11月15日对儿科门诊及住院病儿进行了病原学及临床象观察,报导于下:

【Abstract】 Seventy-seven cases of infantile diarrhea were observed on the etiology and clinical features from 25 Sept. to 15 Nov. 1981.The stool samples of 30 out of 67 cases(44.7%) show rotavirus particles-under the direct electron microscope and with immunofluorescence microscopy.In 16 out of 22 cases the serum titers of CF antibody were elevated 4 folds, it’s positive rate was 60% and the rate of correspondence with electron microscopy and serological examinations was 83.3%.None of the enteric pathogens were positive in the cultures. Routine stool examina tion showed: 1/a lot of fatty droplets in 55.59% of samples, 2/some WBC in 14.7% of samples and a few pus cells in 14.7% of samples, 3/29.31% of samples showed nothing.The clinical features were as follows: All cases had diarrhea with yellowish watery stools and some white curds,sour foul odor, most of the cases(82.35%) had a fre quencay of about 10 times a day. Abdominal pain and distension occurred in about 55.88% of cases, Most cases appeared no water deprivation. Few cases had mild dehy dration(8.82%). and acidosis in 5.85% of cases. Some cases had fever (64.71%)and main tained for 3 days. Half of the cases had respiratory symptoms, manifested as mild nasal discharge, mild cough and congested throat.The course of the disease in most of our patients were about one week. According to our clinical observation, we suggested that the criteria for clinical diagnosis were as fellows.1) Infants of 6-18 months of age got diarrhea during autumn and winter season.2) The sudden onset of vomiting prior or concommitant with yellowish watery stools with curds and with a frequency of around 10 times a day.3) The course of the disease is self-limited.The criteria for final diagnosis were:1) Typical rotavirus particles found under electron microscope.2) Elevation of CF antibody titers of rotavirus, usually 4 folds higher than the first serum sample.

  • 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1982年12期
  • 【被引频次】2
  • 【下载频次】14
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