【摘要】 <正> 从70年代开始,各国学者对乙型肝炎的母婴传播问题进行了大量研究,但国内有关资料还不多。为了解天津市产妇中乙型肝炎病毒(HBV)的感染情况及母婴传播情况、传播机理及有关因素,为乙型肝炎的预防工更多还原

【Abstract】 631 Serum specimens obtained from lying-in women admitted to any one of the four obstetrical departments in Tianjin from March 10 to June 10 1981, were tested for HBsAg by RPHA technique. 25 women had HBsAg (4.0%). 445 cord blood specimens were examined in parallel with their mothers’ blood. Three of 18 cord blood specimens collected from HBsAg-positive mothers were HBsAg-positive, and the other 427 specimens collected from HBsAg-negative mothers were all HBsAg-negative. Of 25 HBsAg-positive mothers, eight had HBeAg, and five had anti-HBe. 27 of the 631 specimens were anti-HBs-positive by PHA technique (4.3%).Some kinds of the secretions obtained from HBsAg-positive women were tested for HBsAg.Thirteen HBsAg-positive mothers and their infants were followed-up after birth for four to six months, all the thirteen mothers remained HBsAg-positive. Among their 13 infants, six became HBsAg-positive (46.2%). Whereas blood of 37 HBsAg-negative mothers’ infants were tested concurrently, and all were HBsAg-negative.There is a close relationship between the titre of HBsAg and/or HBeAg-positive in mothers at child birth time and occurrence of HBsAg in their infants.It is suggested that every woman admitted to the obstetrical department should be examined for HBsAg routinely. The women who carried HBsAg should be treated in isolation, and at the same time protective measures for the baby should be carried out.更多还原