【摘要】 对长期口服“避孕1号”的13名妇女和10名正常对照妇女进行了外周血淋巴细胞培养,比较分析了服药组和对照组的姊妹染色单体互换率(SCE),结果服药组平均每中期相SCE 为9.06±0.33,对照组为8.12±0.27,两组相比无显著意义(P>0.05),表明“避孕1号”不具有可察觉的致突变、致癌效应.更多还原

【Abstract】 The lymphocytes in the peripheral blood of 13 women who had been taking oralcontraceptive tablet Norethindroni Compositae and of 10 normal women who had nevertaken this kind of drug were cultured.Sister chromatid exchange(SCE)frequencies werestudied.The mean SCE frequency((?)±SE) for those women taking oral contraceptives was9.06±0.33 per metaphase,which was not significantly higher than the mean SCE score for10 age.matched controls,8.12±0.27(p>0.05).These data indicate that this kind oforal contraceptive is not a mutagen-carcinogen.更多还原