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DETECTION OF SISTER CHROMATID EXCHANGES IN MOUSE SPERMATOGONIA IN VIVO

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【作者】 吕群江绍慧周洁民蒋秀蓉项维

【Author】 Lü QUN JIANG SHAOHUI ZHOU JIEMIN JIANG XIURONG KIANG WEI (Institute of Genetics, Fudan University, Shanghai)

【机构】 Institute of GeneticsFudan UniversityShanghaiShanghai

【摘要】 <正> Sister chromatid exchanges (SCE) can be detected and a clear demarcation between sister chromatids can be obtained by incorporating 5-bromo-2′-deoxyuridine (BrdU) into chromosomal DNA throughout two rounds of replication period and with the sister chromatid differential staining technique. Numerous experiments have proved that SCEs are very sensitive indicators of mutagens and carcinogens. This test

【关键词】 sisterchromosomalexchangesBrdUbromoindicatorsreplicationinsteadmethanolhasbeen
  • 【文献出处】 A Monthly Journal of Science ,科学通报(英文版) , 编辑部邮箱 ,1982年08期
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